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Anna Herman-Antosiewicz Selected Research

diallyl trisulfide

10/2012Diallyl trisulfide-induced prostate cancer cell death is associated with Akt/PKB dephosphorylation mediated by P-p66shc.
8/2012Impact of JNK1, JNK2, and ligase Itch on reactive oxygen species formation and survival of prostate cancer cells treated with diallyl trisulfide.
8/2011P66Shc mediated ferritin degradation--a novel mechanism of ROS formation.
6/2010Diallyl trisulfide-induced G2/M phase cell cycle arrest in DU145 cells is associated with delayed nuclear translocation of cyclin-dependent kinase 1.
4/2007Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1-dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreventive constituent of processed garlic.
5/2006c-Jun NH(2)-terminal kinase signaling axis regulates diallyl trisulfide-induced generation of reactive oxygen species and cell cycle arrest in human prostate cancer cells.
1/2006Diallyl trisulfide inhibits angiogenic features of human umbilical vein endothelial cells by causing Akt inactivation and down-regulation of VEGF and VEGF-R2.
9/2005Diallyl trisulfide-induced G(2)-M phase cell cycle arrest in human prostate cancer cells is caused by reactive oxygen species-dependent destruction and hyperphosphorylation of Cdc 25 C.
8/2005Checkpoint kinase 1 regulates diallyl trisulfide-induced mitotic arrest in human prostate cancer cells.
11/2004Signal transduction pathways leading to cell cycle arrest and apoptosis induction in cancer cells by Allium vegetable-derived organosulfur compounds: a review.

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Anna Herman-Antosiewicz Research Topics

Disease

24Neoplasms (Cancer)
02/2022 - 06/2004
18Prostatic Neoplasms (Prostate Cancer)
06/2020 - 06/2004
8Breast Neoplasms (Breast Cancer)
02/2022 - 08/2012
5Infections
09/2021 - 03/2001
2Ataxia Telangiectasia (Louis Bar Syndrome)
04/2007 - 06/2004
1Hypoxia (Hypoxemia)
01/2022
1Insulin Resistance
01/2019
1Parkinson Disease (Parkinson's Disease)
01/2019
1Adenocarcinoma
06/2017
1Carcinogenesis
12/2013
1Memory Disorders (Memory Loss)
09/2007
1Mycoses (Diseases, Fungus)
09/2007
1Osteosarcoma (Osteogenic Sarcoma)
04/2007

Drug/Important Bio-Agent (IBA)

12sulforaphaneIBA
03/2017 - 06/2004
10diallyl trisulfideIBA
10/2012 - 11/2004
8Proteins (Proteins, Gene)FDA Link
06/2020 - 03/2001
7Reactive Oxygen Species (Oxygen Radicals)IBA
08/2012 - 06/2004
5IsothiocyanatesIBA
06/2020 - 01/2015
4isothiocyanic acidIBA
10/2017 - 08/2012
4erucinIBA
10/2017 - 01/2015
4Phosphotransferases (Kinase)IBA
01/2015 - 08/2005
3usnic acidIBA
02/2022 - 01/2019
3Anti-Bacterial Agents (Antibiotics)IBA
09/2021 - 01/2014
3IronIBA
01/2019 - 08/2011
3sulphorapheneIBA
06/2017 - 01/2015
3Pharmaceutical PreparationsIBA
03/2017 - 01/2015
3Checkpoint Kinase 2IBA
05/2007 - 06/2004
2Histones (Histone)IBA
01/2022 - 06/2004
2DNA (Deoxyribonucleic Acid)IBA
01/2022 - 06/2004
2Lapatinib (GW572016)FDA Link
03/2017 - 01/2015
2Estrogen ReceptorsIBA
04/2016 - 12/2013
2CarcinogensIBA
09/2007 - 11/2004
2Checkpoint Kinase 1IBA
04/2007 - 08/2005
1IsoxazolesIBA
02/2022
1Radiation-Sensitizing AgentsIBA
01/2022
1Bromodeoxyuridine (BrdU)IBA
01/2022
1Oxygen (Dioxygen)IBA
01/2022
1NucleosidesIBA
01/2022
11,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
06/2020
1AcidsIBA
01/2019
1MyokinesIBA
01/2019
1Insulin (Novolin)FDA Link
01/2019
1Peptide Hydrolases (Proteases)FDA Link
01/2018
1lissamine rhodamine B (sulforhodamine B)IBA
10/2017
1Ribosomal Proteins (Ribosomal Protein)IBA
10/2017
1Ethidium (Ethidium Bromide)IBA
10/2017
1Acridine OrangeIBA
10/2017
1Growth Factor ReceptorsIBA
06/2017
1DAPIIBA
06/2017
1afimoxifene (hydroxytamoxifen)IBA
04/2016
1TamoxifenFDA LinkGeneric
04/2016
1human ERBB2 proteinIBA
01/2015
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2013
1Serine (L-Serine)FDA Link
10/2012
1Ligases (Synthetase)IBA
08/2012
1Ferritins (Ferritin)IBA
08/2011
1Blood Glucose (Blood Sugar)IBA
09/2007
1Anticarcinogenic AgentsIBA
09/2007
1Doxycycline (Periostat)FDA LinkGeneric
04/2007
1SecurinIBA
04/2007
1Cyclin B1IBA
04/2007
1NocodazoleIBA
04/2007
1Cytochromes c (Cytochrome c)IBA
06/2006
1CDC2 Protein Kinase (Protein p34cdc2)IBA
08/2005
1CaspasesIBA
05/2005
1CytochromesIBA
11/2004
1allyl sulfideIBA
11/2004
1diallyl disulfide (diallyl disulphide)IBA
11/2004
1NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)IBA
11/2004
1EnzymesIBA
11/2004
1Mixed Function Oxygenases (Monooxygenases)IBA
11/2004
1Glutathione Transferase (Glutathione S-Transferase)IBA
11/2004
1Membrane Proteins (Integral Membrane Proteins)IBA
05/2002
1CarbohydratesIBA
05/2002
1Bile Acids and Salts (Bile Acids)IBA
05/2002
1AntigensIBA
05/2002

Therapy/Procedure

7Therapeutics
01/2022 - 08/2012
2Chemoprevention
04/2016 - 09/2007
1Radiotherapy
01/2022
1Fluid Therapy (Oral Rehydration Therapy)
09/2021
1Drug Therapy (Chemotherapy)
12/2013